Giáo trình môn di truyền học được viết bởi Daniel L. Hartl Brief Contents Chapter 1 The Molecular Basis of Heredity and Variation Chapter 2 Principles of Genetic Transmission Chapter 3 Genes and Chromosomes Chapter 4 Genetic Linkage and Chromosome Mapping Chapter 5 The Molecular Structure and Replication of the Genetic Material Chapter 6 The Molecular Organization of Chromosomes Chapter 7 Variation in Chromosome Number and Structure Chapter 8 The Genetics of Bacteria and Viruses Chapter 9 Genetic Engineering and Genome Analysis Chapter 10 Gene Expression Chapter 11 Regulation of Gene Activity Chapter 12 The Genetic Control of Development Chapter 13 Mutation, DNA Repair, and Recombination Chapter 14 Extranuclear Inheritance Chapter 15 Population Genetics and Evolution Chapter 16 Quantitative Genetics and Multifactorial Inheritance Chapter 17 Genetics of Biorhythms and Behavior Page iv Contents Preface xv Introduction: For the Student xxi Chapter 1 The Molecular Basis of Heredity and Variation 1-1 DNA: The Genetic Material Experimental Proof of the Genetic Function of DNA Genetic Role of DNA in Bacteriophage 1-2 DNA Structure: The Double Helix 1-3 An Overview of DNA Replication 1-4 Genes and Proteins Transcription of DNA Makes RNA Translation of RNA Makes Protein 1-5 Mutation 1-6 How Genes Determine Traits Pleiotropy: One Gene Can Affect More Than One Trait Epistasis: One Trait Can Be Affected by More Than One Gene Effects of the Environment 1-7 Evolution The Molecular Continuity of Life Adaptation and Diversity The Role of Chance in Evolution Chapter End Material Chapter Summary Key Terms Review the Basics Guide to Problem Solving Analysis and Applications Further Reading Special Features Connection: It's the DNA! Oswald T. Avery, Colin M. MacLeod, and Maclyn McCarty 1944 Studies on the chemical nature of the substance inducing transformation of pneumococcal types Connection: Shear Madness Alfred D. Hershey and Martha Chase 1952 Independent functions of viral protein and nucleic acid in growth of bacteriophage GeNETics on the Web Chapter 2 Principles of Genetic Transmission 2-1 The Monohybrid Crosses Traits Present in the Progeny of the Hybrids Mendel's Genetic Hypothesis and Its Experimental Tests The Principle of Segregation Important Genetic Terminology Verification of Mendelian Segregation by the Testcross 2-2 Segregation of Two or More Genes The Principle of Independent Assortment Dihybrid Testcrosses The Big Experiment 2-3 Mendelian Inheritance and Probability Mutually Exclusive Events: The Addition Rule Independent Events: The Multiplication Rule 2-4 Segregation in Human Pedigrees 2-5 Genetic Analysis The Complementation Test in Gene Identification Why Does the Complementation Test Work? Multiple Alleles 2-6 Modified Dihybrid Ratios Caused by Epistasis 2-7 Complications in the Concept of Dominance Amorphs, Hypomorphs, and Other Types of Mutations Incomplete Dominance Codominance and the Human ABO Blood Groups Incomplete Penetrance and Variable Expressivity Chapter End Material Chapter Summary Key Terms Review the Basics Guide to Problem Solving Analysis and Applications Challenge Problems Further Reading
