Tài liệu Báo cáo y học: "Treat Ankylosing Spondylitis with Methazolamide"

Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease with a prevalence of 0.5–1.9% (1). Spinal inflammation, the hallmark of AS, causes pain and stiffness that leads to progressive spinal deformity and fusion (1). The disease usually takes a chronic course that is characterized by bone resorption and new bone formation with syndesmo-phytes and ankylosis (1). The conventional treatment for AS is mainly based on non-steroidal anti-inflammatory drugs (NSAIDs) and disease modifying anti-rheumatic drugs (DMARDs). Because NSAIDs such as celecoxib