Tài liệu Báo cáo y học: "Serum cholesterol concentration associated with aspirin esterase activity in older p

Aspirin (acetylsalicylic acid) is one of the most frequently used drugs, exploiting its antiinflammatory and anti-platelet actions for the pre-vention of cardiovascular disease (1). Especially, for this purpose, older people are commonly medicated with this agent (2). The so-called ‘aspirin resistance (or aspirin non-responsiveness) syndrome’ is characterized by an incomplete inhibition of platelet function by aspirin (2, 3). It may account for the high variability in effective anti-coagulant doses of aspirin in the population (2, 3)