Tài liệu Báo cáo y học: " Patient Specification Quality Assurance for Glioblastoma Multiforme Brain Tumors Tr

Glioblastoma multiforme (GBM) is the most common malignant tumor of the subcortical white matter of the cerebral hemisphere in adults. It accounts for 12%-15% of all primary brain tumors [1]. The treatment of GBM involves surgical resection, which is the first therapeutic modality for GBM, followed by radiotherapy that may be accompanied by adjuvant chemotherapy [2]. In general, patients with GBM have poor prognosis with about 20% of patients surviving beyond 2 years [2]. However, some factors may be associated with a longer survival rate. These factors include younger age, gender, unilateral tumor, a high Karnofsky score, size of the tumor, extent of disease, and adjuvant treatments with chemotherapy such as temozolomide (TMZ) [3].