Tài liệu Báo cáo y học: "Optimization of 5-fluorouracil solid-lipid nanoparticles: a preliminary study to tre

Colorectal cancer is the second leading cause of cancer related death for men and women worldwide. Each year there are about one million new cases of colorectal cancer. Its incidence has increased over the last 25 years [1]. Colorectal cancer is a disease that is manifested by the formation of adenomatous polyps and malignant cells in the colon [2]. These abnormal cells creating tumors are characterized by unregulated replication and the capability of spreading to other sites [2].