Tài liệu Báo cáo y học: "High-Resolution Flow Cytometry: a Suitable Tool for Monitoring Aneuploid Prostate Ca

Prostate cancer (PCa) is the most common solid tumor in men. In 2007, there will be approximately 220.000 men diagnosed with prostate cancer in the U.S. [1]. The annual incidence of the male population in West-Europe and the U.S.A averages approximately 88 per 100.000 men [2]. As the wide range of the PCa’s aggressiveness shows: while some patients are being able to live symptom-free and without any treatment for many years, there are aggressive forms with rapid growth and early metastatic spreading. The current therapeutic options in the treatment of PCa are: i) Radical excision of prostate and seminal vesicles [3, 4]. ii) Percutaneous radiation therapy with high energetic photons (6-23 MeV) [5, 6]. iii) Interstitial radiation therapy with temporarily or permanent radioactive implants (brachytherapy) [7]. iv) The standard initial systemic therapy for locally advanced or metastatic disease is hormonal or androgen deprivation therapy (ADT) that may be performed by bilateral orchiectomy or pharmaceutical means.