Tài liệu Báo cáo y học: "Antimicrobial Susceptibilities of Brucella Isolates from Various Clinical Speciemens

Human brucellosis remains the most common zoonotic disease worldwide, with more than 500,000 new cases annually [1]. It is caused by Gram-negative bacteria, Brucella spp. and is transmissible to humans through direct contact with infected animals, con-sumption of dairy products, or inhalation of aerosols [2]. Brucellosis is a multisystemic disease that shows wide clinical polymorphism. Its main clinical signs are fever, headache, anorexia, fatigue, arthritis, hepato-splenomegaly, and neurological signs [2]. The disease represents serious consequences for public health by long treatment, slow recovery and possible serious sequelae in the locomotive and nervous system [2]. Although brucellosis has been eradicated in many northern European countries, in Australia, New Zealand, and Canada due to the implementation of national surveillance program and vaccination of live