Tài liệu Báo cáo y học: "A k2A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt’

Klebsiella pneumoniae is often isolated in hospi talacquired urinary tract infections, septicemias, pneumonia, and intra-abdominal infections [1]. Although bacterial liver abscesses are rare, K. pneumoniae is one of the leading etiologic agents [2]. Since 1981, a distinct clinical syndrome of septicemia with liver abscess and metastatic infections due to K. pneumoniae has emerged, with a predominance of cases in Taiwan [3-6]. The invasive K. pneumoniae liver isolates associated with this syndrome more often exhibited a hypermucoviscosity and belong to either the serotype K1 or K2 [5, 6]. The presence of a mucoviscosity associated gene A (magA) has also been shown to more prevalent in strains isolated from human liver ab-scesses and are only associated with the K1 serotype [7]. The presence of the K2 capsule-associated gene A (k2A) is associated with K2 isolates which are also hypervirulent [8]. We report the first case of a hypervirulent non-magA, K2 K. pneumoniae liver isolate found in a man from Saint Kitts, a Caribbean island.