Tài liệu Báo cáo khoa học: "The role of cardiac troponin I as a prognosticator in critically ill medical pati

Assessing the severity of illness and outcome of critically ill patients is important as it influences management strategies and resource allocation. Historically, research aimed at determining factors associated with intensive care unit (ICU) mortality focused on individual risk factors and the development of multivariable prediction scores. These investigations consistently suggested the importance of organ system failure as strong predictors of both ICU and hospital mortality [1-4]. Over the past decade, several studies indicated that cardiac dysfunction is a frequent and important factor in determining the outcome of critically ill patients [5,6]. The pathophysiology of myocardial injury in critically ill patients is believed to be multifactorial, including the underlying disease process, hypoxemia and acidosis as well as therapeutic maneuvers [7,8]. It is estimated that as many as 15% of ICU admissions are compli-